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Monday, 12 August 2019

Can we use bugs as drugs (conclusion)? by Professor Emma Allen-Vercoe, Dept of Molecular and Cellular Biology Continues notes. Guelph Conference

Can we add beneficial microbes back? Probiotics from the drug/health store? Generally it is very safe and defined. Industry is poorly regulated. Effects are modest at best. There is much hype but little scientific proof. Faecal transplants? Have shown great promise in treating gut infections. There are many unknowns. It is difficult to figure out the therapeutic effects. It is rather disgusting. A hybrid study? Instead of stool, why not use pure microbes, isolated from the gut of a healthy person? Major barriers to cultivation are low abundance and fastidiousness. Someone needs to take the first step. There is a new framework being developed in what Prof Emma Allen-Vercoe considers in research the stability, diversity, functionality, and strain interactivity - The needs of the interactivity of the ecosystem. It needs to be commercialized; Needs of the patient: oral preferred. Coming soon - Met - 2 is a new first class biologic drug - lyophilized, standardized, ecosystem for oral delivery; Clinical c. difficile. Faecal transplant is already a thing and Canada Health is concerned about it. Regarding advertisement: Yoghurt probiotics - no. www.probiotic chart.ca has a list of all evidence that are legitimate. 99% sold is all rubbish. Read the small print.

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